Increased uric acid is the main cause of gout
Uric acid is produced by the liver to outputfrom the body of excess nitrogen. This component is present in the blood in the form of a sodium salt and is the final product of protein metabolism. In case of violations of the kidneys, an increase in the concentration of this substance occurs, which leads to various damages to tissues and organs. Often, increased uric acid provokes the development of renal stone disease and kidney failure, and its excess quantity is deposited in the cartilaginous tissue and joints, leading to painful inflammatory processes.
Norms of uric acid in the body
With a normal lifestyle and a balancedthe human body must produce up to 600 g of uric acid daily. The third part of this amount is excreted through the intestine, and the rest is excreted together with the urine. In men, the concentration of uric acid is within the limits of 55 mg per liter, and in women this mark should not exceed 40 mg, but the onset of menopause may slightly increase this figure. It should be noted that hyperuricemia is more common in men due to non-compliance with the rules of healthy eating.
Uric acid is a very important indicator of the state of human health, so its study to date is used widely enough by specialists of various profiles.However, for more reliable indicators beforethe patient must observe certain rules by taking biological material. 12 hours before the uric acid test, you should refrain from eating, completely eliminate all drinks except water, and give up alcohol and cigarettes. In addition, for 2-3 days, you must follow a diet that contains the minimum amount of purine. This means that the patient needs to give up beans, coffee, chocolate, red meat, liver, kidneys and tongue. Blood sampling is carried out on an empty stomach, and elevated uric acid is determined by the enzymatic method, it is simple enough, reliable and convenient.
Causes of ailment
Increased uric acid can be detected even in the body of a healthy person with prolonged fasting, physical exertion or the use of food rich in purines.In addition, in pregnant women suffering fromstrong toxicosis, hyperuricemia can also be observed. A pathological increase in the amount of uric acid is a sign of gout - a disease in which the kidneys remove only a part of this substance, and the rest is crystallized and deposited in the eyes, skin, joints, kidneys, heart and intestines. As a rule, this disease is inherited, in other cases it develops as a result of malnutrition. Often, increased uric acid is observed with obesity, heart failure, blood diseases, hepatitis, pneumonia, tuberculosis, psoriasis, eczema and pathologies of the biliary tract.
The concentration of this substance can be lowered withusing medications, otherwise complications such as gout development, stone deposition, increased blood pressure, cardiac arrhythmias, angina pectoris development, and even myocardial infarction are possible.