Postinor - instructions for use

Tablets postinor, whose instructions are given, are available in white or whitish color. Tablets in the form of a flat disc, on one side marked "INOR".

Composition

Active substance:

  • levonorgestrel 750 μg (in 1 tablet).

Excipients:

  • potato starch;
  • lactose monohydrate;
  • anhydrous colloidal silica dioxide;
  • talc;
  • magnesium stearate;
  • corn starch.

Pharmacological action of the drug

Synthetic drug, contraceptive(emergency), which affects the function of the pituitary gland, reducing the amount of FSH and LH produced by it. In addition, the drug disrupts the metabolism of the endometrium, as a result of which the implantation of the egg is broken. The amount of cervical mucus increases, preventing the progress of spermatozoa, after taking the drug postinor.

Instructions on the pharmacological effect of the drug is given in abbreviated form, for more precise information, refer to the official annotation of the drug.

Pharmacokinetics

The drug is absorbed quickly enough by their digestive tract. Postinor is metabolized in the liver, at the first passage through it, with the formation of glucuronide and sulfate conjugates. Metabolites are excreted mainly with urine, but can also be excreted through the intestine.

Indications

The drug is intended primarily as a means of emergency hormonal contraception. It can also be used in combination therapy as a means of hormone replacement therapy.

Contraindications

  • pregnancy;
  • neoplasms of the mammary gland, as well as genital organs;
  • uterine bleeding;
  • liver tumors;
  • liver disease in acute phase;
  • thrombophlebitis;
  • thromboembolic disorders;
  • coronary artery disease;
  • cerebrovascular diseases;
  • sensitiveness to levonorgestrel.

In addition, in all patients who are overweight, the effectiveness of the drug can be reduced.

Side effects of the drug postinore

The instruction contains exhaustive data on the side effects that may occur after applying the pasteurore.

Possible side effects of the drug on the part of the digestive tract:

  • vomiting;
  • nausea;
  • cramps in the abdomen;
  • flatulence.

Possible side effects of using the drug from the genitourinary system:

  • dysmenorrhea;
  • changes in the process of menstruation (duration, intensity);
  • discharge of milky color;
  • pathology of cervical secretion;
  • vaginal candidiasis.

Possible side effects of the drug on the part of the body's metabolism:

  • change in body weight.

Possible side effects from the use of the drug from the possible manifestation of allergic reactions:

  • only skin rash

In addition, this drug is oftencauses a hormonal failure in the body, so if after receiving it there are long-term intermenstrual blood discharges, then you need to see a doctor for a survey.

Drug Interactions of Postinor

Instruction for use states thatThe contraceptive effect of the drug is reduced if primidone, rifampicin, barbiturates, phenytoin are taken at the same time. This is due to the fact that these drugs increase the level of steroids.

Increased intermenstrual bleedingit is possible if neomycin, nitrofurantoin, chloramphenicol, sulfamethoxypyridazine, ampicillin, phenoxymethylpenicillin are used simultaneously with the postinor.

Postinor, the instruction confirms this, while using it reduces the effectiveness of hypoglycemic, antihypertensive, anticonvulsants and anticoagulants.

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